Chemodiversity Associated with Cytotoxicity and Antimicrobial Activity of Piper aduncum var. ossanum
Identifieur interne : 000E23 ( Main/Exploration ); précédent : 000E22; suivant : 000E24Chemodiversity Associated with Cytotoxicity and Antimicrobial Activity of Piper aduncum var. ossanum
Auteurs : Yamilet Gutiérrez [Cuba] ; Rodny Montes [Cuba] ; Ram N Scull [Cuba] ; Arturo Sánchez [Cuba] ; Paul Cos ; Lianet Monzote [Cuba] ; William N. Setzer [États-Unis]Source :
- Chemistry & Biodiversity [ 1612-1872 ] ; 2016-12.
Abstract
Chemical analysis, antimicrobial activity and cytotoxic effects of essential oils (EOs) from leaves of Piper aduncum var. ossanum from two localities Bauta (EO‐B) and Ceiba (EO‐C), Artemisa Province, Cuba, were determined. EOs were obtained by hydrodistillation and analyzed by gas chromatography/mass spectrometry. EO‐B demonstrated higher activity against S. aureus and L. amazonensis; while a lower cytotoxicity on mammalian cells was observed. Both EOs displayed the same activity against Plasmodium falciparum, Trypanosoma cruzi, Trypanosoma brucei, and Leishmania infantum. Both EOs were inactive against Escherichia coli and Candida albicans.
Url:
DOI: 10.1002/cbdv.201600133
Affiliations:
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EOs were obtained by hydrodistillation and analyzed by gas chromatography/mass spectrometry. EO‐B demonstrated higher activity against S. aureus and L. amazonensis; while a lower cytotoxicity on mammalian cells was observed. Both EOs displayed the same activity against Plasmodium falciparum, Trypanosoma cruzi, Trypanosoma brucei, and Leishmania infantum. 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